Blapsin B
Product Specifications
CAS Number
861145-00-8
Target
Others
Related Pathways
Others
Bioactivity
Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC (50) value of 10.0 ?M as determined by an ELISA assay, and 2.5 ?M in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.
Smiles
OC=1C=C2C(OCCC2=CC1O)C3=CC(O)=C(O)C=C3
Molecular Formula
C15H14O5
Molecular Weight
274.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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