Apilimod 2HCl
Product Specifications
CAS Number
870087-37-9
Target
IL Receptor, Pyroptosis, NOD-like Receptor (NLR), PI3K
Related Pathways
Apoptosis, Immunology/Inflammation, PI3K/Akt/mTOR signaling
Purity
0.9841
Bioactivity
Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation, IL-1β secretion, and cellular pyroptosis, and is used in the study of amyotrophic lateral sclerosis.
Smiles
CC1=CC(/C=N/NC2=NC(OCCC3=NC=CC=C3)=NC(N4CCOCC4)=C2)=CC=C1.Cl.Cl
Molecular Formula
C23H28Cl2N6O2
Molecular Weight
491.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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