Cilazapril HCl
Product Specifications
CAS Number
88824-78-6
Target
Others, Angiotensin-converting Enzyme (ACE)
Related Pathways
Others, Metabolism
Bioactivity
Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension. Cilazapril is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. Cilazapril is a monoethyl ester, which acts as an angiotensin-converting enzyme (ACE) inhibitor. The inhibitor functions by inhibiting the ability of ACE to cleave bonds of angiotensin I and Hip-His-Leu. It is known that the diacid form of Cilazapril is more potent that enalapril at inhibiting ACE.
Smiles
Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCCN2CCC[C@H](N2C1=O)C(O)=O
Molecular Formula
C22H32ClN3O5
Molecular Weight
453.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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