Mafosfamide
Product Specifications
CAS Number
88859-04-5
Target
Others
Related Pathways
Others
Bioactivity
Mafosfamide is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, mafosfamide, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, mafosfamide is potentially useful in the intrathecal treatment of neoplastic meningitis.
Smiles
N(CCCl)(CCCl)P1(=O)N[C@H](SCCS(=O)(=O)O)CCO1
Molecular Formula
C9H19Cl2N2O5PS2
Molecular Weight
401.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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