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AMG-1

Product Specifications

CAS Number

903591-53-7

Target

Calcium Channel, Others

Related Pathways

Others, Membrane transporter/Ion channel, Metabolism

Bioactivity

AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo.

Smiles

ClC=1C(=CC(C(F)(F)F)=CC1)C=2C=NC(NC(=O)C3=C(F)C=CC=C3F)=CN2

Molecular Formula

C18H9ClF5N3O

Molecular Weight

413.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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