AMG-1
Product Specifications
CAS Number
903591-53-7
Target
Calcium Channel, Others
Related Pathways
Others, Membrane transporter/Ion channel, Metabolism
Bioactivity
AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo.
Smiles
ClC=1C(=CC(C(F)(F)F)=CC1)C=2C=NC(NC(=O)C3=C(F)C=CC=C3F)=CN2
Molecular Formula
C18H9ClF5N3O
Molecular Weight
413.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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