A-849519
Product Specifications
CAS Number
904680-01-9
Target
Others
Related Pathways
Others
Bioactivity
A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.
Smiles
C(O)(=O)C1=C2C(=CC=C1NS(=O)(=O)C3=C(/C=C\CN(C)C)C=C(F)C=C3)CCCC2
Molecular Formula
C22H25FN2O4S
Molecular Weight
432.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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