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Piroxantrone

Product Specifications

CAS Number

91441-23-5

Target

Others|||Topoisomerase

Related Pathways

Others|||DNA Damage/DNA Repair

Bioactivity

Piroxantrone, also known as CI942; PD111815, is a n anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity.

Smiles

N(CCCN)C1=C2C=3C(C=4C(C2=O)=C(O)C=CC4O)=NN(CCNCCO)C3C=C1

Molecular Formula

C21H25N5O4

Molecular Weight

411.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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