AGG-523
Product Specifications
CAS Number
920289-29-8
Target
Others, Protease
Related Pathways
Others, Proteases/Proteasome
Bioactivity
AGG-523 is an aggrecanase specific inhibitor that has been shown to attenuate increases in synovial fluid ARG-aggrecan levels following surgically-induced joint instability in the rat MT model. Pharmacologic inhibition of aggrecanase activity in humans using AGG-523 may be an effective treatment for slowing cartilage degradation following joint injury.
Smiles
C(N[C@H](C(NC(CC1=CC=C(F)C=C1)(C)C)=O)CCC(O)=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3
Molecular Formula
C28H29FN2O4
Molecular Weight
476.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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