BMS-751324
Product Specifications
CAS Number
948842-66-8
Target
P38 MAPK, Others, TNF
Related Pathways
Apoptosis, MAPK, Others
Bioactivity
BMS-751324, a p38α MAPK inhibitor, features a carbamyl-methyl linkage precursor with esters and phosphate functional groups from hydroxyphenylacetic acid (HPA) . It effectively reduces foot swelling and suppresses LPS-induced TNFα production in an arthritic rat model.
Smiles
N(C=1C=2N(C=C(C(N(C(OCOC(CC3=CC=C(OP(=O)(O)O)C=C3)=O)=O)CCC)=O)C2C)N=CN1)C4=CC(C(NC5CC5)=O)=CC=C4C
Molecular Formula
C32H35N6O10P
Molecular Weight
694.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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