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Fc 11a-2

Product Specifications

CAS Number

960119-75-9

Target

NOD-like Receptor (NLR), Others

Related Pathways

Others, Immunology/Inflammation

Bioactivity

Fc 11a-2, a benzimidazole compound, functions as an orally active, potent inhibitor of the NLRP3 inflammasome by blocking caspase-1 activation and thus preventing the activation of IL-1β/IL-18. Additionally, Fc 11a-2 inhibits the progression of Dextran sulfate sodium (DSS) -induced murine experimental colitis [1] [2] [3].

Smiles

C(C)N1C(=NC=2C1=CC=C(C)C2)C3=CC=CC=C3

Molecular Formula

C16H16N2

Molecular Weight

236.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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