Fc 11a-2
Product Specifications
CAS Number
960119-75-9
Target
NOD-like Receptor (NLR), Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Fc 11a-2, a benzimidazole compound, functions as an orally active, potent inhibitor of the NLRP3 inflammasome by blocking caspase-1 activation and thus preventing the activation of IL-1β/IL-18. Additionally, Fc 11a-2 inhibits the progression of Dextran sulfate sodium (DSS) -induced murine experimental colitis [1] [2] [3].
Smiles
C(C)N1C(=NC=2C1=CC=C(C)C2)C3=CC=CC=C3
Molecular Formula
C16H16N2
Molecular Weight
236.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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