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Saterinone

Product Specifications

CAS Number

102669-89-6

Target

PDE, Adrenergic Receptor

Related Pathways

Neuroscience, GPCR/G Protein, Metabolism

Purity

>99.99%

Bioactivity

Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic heart failure. Saterinone inhibited crude cAMP phosphodiesterase (PDE) activity in guinea pig right ventricular homogenates The ic50 value is 2.3 x 10 (-5) mol/l.

Smiles

CC1=C(C=C(C#N)C(=O)N1)C2=CC=C(OCC(CN3CCN(CC3)C4=C(OC)C=CC=C4)O)C=C2

Molecular Formula

C27H30N4O4

Molecular Weight

474.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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