Oxodipine
Product Specifications
CAS Number
90729-41-2
Target
Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Metabolism
Purity
0.9964
Bioactivity
Oxodipine, a dihydropyridine-type calcium antagonist, inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduced L-type Ca currents (I) with an IC of 0.24 μM, and against T-type Ca currents (I) with an IC of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs.
Smiles
C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C3C(=CC=C2)OCO3
Molecular Formula
C19H21NO6
Molecular Weight
359.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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