Litoxetine
Product Specifications
CAS Number
86811-09-8
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9968
Bioactivity
Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently reduced the number of regurgitations and vomiting and delayed the onset of vomiting. Litoxetine has an affinity for brain 5HT3 receptors (Ki = 85 nM) .
Smiles
C(OC1CCNCC1)C2=CC3=C(C=C2)C=CC=C3
Molecular Formula
C16H19NO
Molecular Weight
241.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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