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JB062

Product Specifications

CAS Number

2417988-00-0

Target

Myosin

Related Pathways

Cytoskeletal Signaling

Purity

0.9989

Bioactivity

JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It selectively exhibits cytotoxicity towards human cancer cells without affecting normal cells. The compound is applicable in research fields concerning muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.

Smiles

OC=1C=2C(OC(=O)C1C(=NCC3=CC=C(OC)C=C3)C)=CC=CC2

Molecular Formula

C19H17NO4

Molecular Weight

323.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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