JB062
Product Specifications
CAS Number
2417988-00-0
Target
Myosin
Related Pathways
Cytoskeletal Signaling
Purity
0.9989
Bioactivity
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It selectively exhibits cytotoxicity towards human cancer cells without affecting normal cells. The compound is applicable in research fields concerning muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
Smiles
OC=1C=2C(OC(=O)C1C(=NCC3=CC=C(OC)C=C3)C)=CC=CC2
Molecular Formula
C19H17NO4
Molecular Weight
323.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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