ML353
Product Specifications
Target
GluR, Potassium Channel
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9998
Bioactivity
ML353 (VU0478006) is a selective activator of TREK-1 and TREK-2 and a selective ligand (Ki =18.2 nM) for the mGlu5 Silencing Allosteric Modulator (SAM) . ML353 has potential as a solution to the intrinsic activity or pharmacological blockade of SAM in vivo.
Smiles
O=C(C1=NC=C(C#CC2=CC(F)=CC=C2)C=C1)N1CC2CC2C1
Molecular Formula
C19H15FN2O
Molecular Weight
306.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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