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USP8-IN-2

Product Specifications

CAS Number

2477651-11-7

Target

DUB

Related Pathways

DNA Damage/DNA Repair, Ubiquitination, Cell Cycle/Checkpoint

Purity

0.9992

Bioactivity

USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.

Smiles

C(F)(F)(F)C1=NC(=CC=C1)N2CCC(NC(NC3=C(OC)C=CC(Cl)=C3)=S)CC2

Molecular Formula

C19H20ClF3N4OS

Molecular Weight

444.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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