What is the catalog number for AT-533?

The catalog number for AT-533 is T67836.

What sizes are available for AT-533?

AT-533 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does AT-533 come in?

AT-533 is available in 8 different pack sizes.

AT-533 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AT-533?

AT-533 is manufactured by Molfinity.

What is the estimated delivery time for AT-533?

Estimated delivery time for AT-533 is approximately 10 business day(s), depending on your location.

AT-533

Product Specifications

CAS Number

908112-37-8

Target

VEGFR, NF-κB, Akt, HSP, ERK, HIF/HIF Prolyl-Hydroxylase, FAK, HSV

Related Pathways

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Metabolism, Microbiology/Virology, Tyrosine Kinase/Adaptors, NF-κB, Angiogenesis, MAPK, Chromatin/Epigenetic

Purity

0.9967

Bioactivity

AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, including Erk1/2, FAK, Akt/mTOR/p70S6K, . AT-533 inhibits the cell migration, invasion, and the tube formation of human umbilical vein endothelial cells (HUVECs) .