HIF-2α agonist 2
Product Specifications
CAS Number
2750141-15-0
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Chromatin/Epigenetic, Angiogenesis
Purity
0.9927
Bioactivity
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reha-Luc cells. HIF-2α agonist 2 can be used in the study of oxygen metabolism and is closely related to the occurrence of cancer.
Smiles
N(C=1C=2C(S(=O)(=O)N1)=CC=CC2)C3=CC(Br)=CC(Br)=C3
Molecular Formula
C13H8Br2N2O2S
Molecular Weight
416.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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