Enpp/Carbonic anhydrase-IN-1
Product Specifications
CAS Number
2883495-35-8
Target
Carbonic Anhydrase, Apoptosis, PDE
Related Pathways
Metabolism, Apoptosis
Purity
>99.99%
Bioactivity
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase, exhibiting IC50s of 1.36, 1.35, 3.00, 0.88, and 1.02 μM for NPP1, NPP2, NPP3, CA-II, and CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 also demonstrates selective antiproliferative activity for cancer cells.
Smiles
O=C(Nc1ccc(OS(=O)(=O)c2ccccc2)cc1)C12CC3CC(CC(C3)C1)C2
Molecular Formula
C23H25NO4S
Molecular Weight
411.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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