Cholesteryl Hemisuccinate
Product Specifications
CAS Number
1510-21-0
Target
DNA/RNA Synthesis, Apoptosis, Necroptosis, Topoisomerase
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis
Purity
0.9998
Bioactivity
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl Hemisuccinate inhibits the hepatotoxicity of acetaminophen and prevents AAP-induced apoptosis and necrosis in hepatocytes. Cholesteryl Hemisuccinate inhibits DNA polymerase and DNA topoisomerase, thereby inhibiting DNA replication and repair as well as cell division.
Smiles
[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCC(O)=O
Molecular Formula
C31H50O4
Molecular Weight
486.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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