Menin-MLL inhibitor 21
Product Specifications
Target
Histone Methyltransferase|||Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9995
Bioactivity
Menin-mll inhibitor 21 is a selective, oral and irreversible Menin inhibitor. Menin-MLL inhibitor 21 promotes selective proliferation of ? cells and improvement of ? cell function in human islet cultures in vitro. Menin-MLL inhibitor 21 enhances glycemic control in animal models of diabetes. Menin-MLL inhibitor 21 induced a dose-dependent increase in insulin secretion that was augmented by a GLP-1 receptor agonist (RA) .
Smiles
N(C(=O)C1=CC(CN2C[C@H](NC(C=C)=O)CCC2)=CC=N1)C3=CC=C(C4=CC5=C(N=CN=C5N4)N6CCOCC6)C=C3
Molecular Formula
C31H34N8O3
Molecular Weight
566.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/701354EA-57BE-4FB1-8C6E-A5A49D16AD80/T64381
CAS Number
2448172-22-1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
