Laniquidar TFA
Product Specifications
Target
P-gp
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Purity
0.9985
Bioactivity
Laniquidar TFA (R101933) is a novel orally available non-competitive P-glycoprotein (P-gp) inhibitor with an IC50 value of 0.51 ?M.Laniquidar has limited bioavailability and can be used to modulate the multidrug resistance transporter.Laniquidar can be used for the study of AML and myelodysplastic syndrome (MDS) . Laniquidar is used to study acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) .
Smiles
O=C(C1=CN=C2/C(C3=C(CCN21)C=CC=C3)=C4CCN(CC\4)CCC5=CC=C(C=C5)OCC6=NC7=C(C=C6)C=CC=C7)OC.OC(C(F)(F)F)=O
Molecular Formula
C39H37F3N4O5
Molecular Weight
698.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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