LDN-193189 Tetrahydrochloride
Product Specifications
CAS Number
2310134-98-4
Target
ALK, TGF-beta/Smad
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells
Purity
0.9821
Bioactivity
LDN-193189 Tetrahydrochloride (DM-3189 Tetrahydrochloride) is a selective inhibitor of BMP type I receptors, inhibiting ALK2 and ALK3 (IC50 = 5/30 nM), with weaker activity against ALK4, ALK5, and ALK7, and can be used for research into progressive osseous fibrodysplasia.
Smiles
C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=C6C=CC=CC6=NC=C1.Cl.Cl.Cl.Cl
Molecular Formula
C25H26Cl4N6
Molecular Weight
552.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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