TUG-499
Product Specifications
CAS Number
1206629-08-4
Target
PPAR, GPCR
Related Pathways
Endocrinology/Hormones, GPCR/G Protein, Metabolism, DNA Damage/DNA Repair
Purity
0.9993
Bioactivity
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39) . It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARγ, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes.
Smiles
C(#CC1=CC=C(CCC(O)=O)C=C1)C=2C=C(Cl)N=C(Cl)C2
Molecular Formula
C16H11Cl2NO2
Molecular Weight
320.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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