TAPI1 acetate
Product Specifications
Target
MMP
Related Pathways
Proteases/Proteasome
Purity
0.9994
Bioactivity
TAPI1 acetate is a salt form of TAPI1. TAPI1 (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α, TNFRI (p60), and TNFRII (p80), IL-6 other cytokine receptors; TAPI-1 is also a metalloproteinase MMP inhibitor that promotes cisplatin-induced ESCC cell apoptosis by inhibiting the NF-κB signaling pathway to promote cisplatin-induced apoptosis in ESCC cells.
Smiles
CC(C[C@@H](C(N[C@H](C(N[C@H](C(NCCN)=O)C)=O)Cc(cc1)cc2c1cccc2)=O)CC(NO)=O)C.CC(O)=O
Molecular Formula
C28H41N5O7
Molecular Weight
559.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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