Mithramycin A
Product Specifications
CAS Number
18378-89-7
Target
DNA/RNA Synthesis, GST, Antibacterial, Antibiotic
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Oxidation-Reduction, Microbiology/Virology
Purity
0.9992
Bioactivity
Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.
Smiles
[H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@]([H])(Oc2cc3cc4C[C@@]([H])([C@H](OC)C(=O)[C@@H](O)[C@@H](C)O)[C@H](O[C@@]5([H])C[C@@H](O[C@@]6([H])C[C@@H](O[C@@]7([H])C[C@](C)(O)[C@H](O)[C@@H](C)O7)[C@@H](O)[C@@H](C)O6)[C@H](O)[C@@H](C)O5)C(=O)c4c(O)c3c(O)c2C)O[C@H](C)[C@H]1O
Molecular Formula
C52H76O24
Molecular Weight
1085.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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