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Mithramycin A

Product Specifications

Target

DNA/RNA Synthesis|||GST|||Antibacterial|||Antibiotic

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Oxidation-Reduction|||Microbiology/Virology

Purity

0.9992

Bioactivity

Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.

Smiles

[H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@]([H])(Oc2cc3cc4C[C@@]([H])([C@H](OC)C(=O)[C@@H](O)[C@@H](C)O)[C@H](O[C@@]5([H])C[C@@H](O[C@@]6([H])C[C@@H](O[C@@]7([H])C[C@](C)(O)[C@H](O)[C@@H](C)O7)[C@@H](O)[C@@H](C)O6)[C@H](O)[C@@H](C)O5)C(=O)c4c(O)c3c(O)c2C)O[C@H](C)[C@H]1O

Molecular Formula

C52H76O24

Molecular Weight

1085.15

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/6A99AE63-DA7A-4474-A89F-C28E8EF0C553/T5530

CAS Number

18378-89-7

Available Sizes

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