Mithramycin A

Product Specifications

CAS Number

18378-89-7

Target

DNA/RNA Synthesis|||GST|||Antibacterial|||Antibiotic

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Oxidation-Reduction|||Microbiology/Virology

Purity

0.9992

Bioactivity

Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.

Smiles

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