QL-X-138 HCl
Product Specifications
Target
MNK, BTK
Related Pathways
Angiogenesis, MAPK, Tyrosine Kinase/Adaptors
Purity
0.9925
Bioactivity
QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK. QL-X-138 HCl inhibited BTK, MNK1, and MNK2 kinases. QL-X-138 HCl has anti-dengue virus 2 activity and shows anti-proliferative activity in acute myeloid leukemia cells. QL-X-138 HCl can be used to study lymphoma and leukemia.
Smiles
O=C(NC1=CC(N2C(C=CC3=CN=C4C=CC(C5=CNN=C5)=CC4=C32)=O)=CC=C1C)C=C.Cl[H]
Molecular Formula
C25H20ClN5O2
Molecular Weight
457.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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