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QL-X-138 HCl

Product Specifications

Target

MNK, BTK

Related Pathways

Angiogenesis, MAPK, Tyrosine Kinase/Adaptors

Purity

0.9925

Bioactivity

QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK. QL-X-138 HCl inhibited BTK, MNK1, and MNK2 kinases. QL-X-138 HCl has anti-dengue virus 2 activity and shows anti-proliferative activity in acute myeloid leukemia cells. QL-X-138 HCl can be used to study lymphoma and leukemia.

Smiles

O=C(NC1=CC(N2C(C=CC3=CN=C4C=CC(C5=CNN=C5)=CC4=C32)=O)=CC=C1C)C=C.Cl[H]

Molecular Formula

C25H20ClN5O2

Molecular Weight

457.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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