Tetranor-12 (R) -HETE

Metabolism of 12 (R) -HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1. This metabolite is 8 (R) -hydroxy hexadecatrienoic acid (8 (R) -HHxTrE) or 2,3,4,5-tetranor 12 (R) -HETE.