Tetrac
Product Specifications
CAS Number
67-30-1
Target
EGFR, Integrin, Apoptosis, Endogenous Metabolite
Related Pathways
Angiogenesis, Cytoskeletal Signaling, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Metabolism, Apoptosis
Purity
0.9904
Bioactivity
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac blocks the effects of T4 and 3,5,3'-triiodo-L-thyronine (T3) on the cell-surface thyroxine integrin αvβ3 receptors.Tetra has anti-angiogenic, anti-tumor activity and pro-apoptotic activity.
Smiles
OC(=O)Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1
Molecular Formula
C14H8I4O4
Molecular Weight
747.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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