Tetrachlorohydroquinone
Product Specifications
CAS Number
87-87-6
Target
Necroptosis|||Reactive Oxygen Species|||Apoptosis|||ROS|||Drug Metabolite|||Others
Related Pathways
NF-?B|||Others|||Apoptosis|||Immunology/Inflammation|||Metabolism
Bioactivity
Tetrachlorohydroquinone (TCHQ), a metabolite of the organochlorine biocide pentachlorophenol, is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 ?M in a neutral red assay) . TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of mitochondrial membrane potential and necrosis in splenocytes.
Smiles
Oc1c(Cl)c(Cl)c(O)c(Cl)c1Cl
Molecular Formula
C6H2Cl4O2
Molecular Weight
247.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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