(Rac) -PF-4136309 (1341224-83-6 Free base)
Product Specifications
CAS Number
857679-55-1
Target
Others, CCR
Related Pathways
Others, GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology
Bioactivity
PF-4136309 (INCB8761, PF-04136309) is a highly effective and selective oral CCR2 antagonist with good bioavailability, with an IC50 value of 5.2 nM for human CCR2.
Smiles
O=C(NC1=NC=C2C=CC(=CC2=C1)C=3C=NN(C3)C)C=4C=CN=C(C4)N5CCN(C)CC5
Molecular Formula
C29H31F3N6O3
Molecular Weight
568.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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