Bazedoxifene
Product Specifications
CAS Number
198481-32-2
Target
IL Receptor, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Others
Related Pathways
Endocrinology/Hormones, Others, Immunology/Inflammation
Purity
0.9879
Bioactivity
Bazedoxifene is a non-steroidal, orally active selective estrogen receptor modulator that exhibits activity against ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. Bazedoxifene also inhibits IL-6/GP130 protein interactions. Bazedoxifene is utilized in research on postmenopausal osteoporosis and pancreatic cancer, serving as a dual-purpose compound for hormonal and cytokine pathway investigations.
Smiles
OC=1C=CC(=CC1)C2=C(C3=CC(O)=CC=C3N2CC4=CC=C(OCCN5CCCCCC5)C=C4)C
Molecular Formula
C30H34N2O3
Molecular Weight
470.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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