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Bazedoxifene

Product Specifications

CAS Number

198481-32-2

Target

IL Receptor, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Others

Related Pathways

Endocrinology/Hormones, Others, Immunology/Inflammation

Purity

0.9879

Bioactivity

Bazedoxifene is a non-steroidal, orally active selective estrogen receptor modulator that exhibits activity against ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. Bazedoxifene also inhibits IL-6/GP130 protein interactions. Bazedoxifene is utilized in research on postmenopausal osteoporosis and pancreatic cancer, serving as a dual-purpose compound for hormonal and cytokine pathway investigations.

Smiles

OC=1C=CC(=CC1)C2=C(C3=CC(O)=CC=C3N2CC4=CC=C(OCCN5CCCCCC5)C=C4)C

Molecular Formula

C30H34N2O3

Molecular Weight

470.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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