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Otaplimastat HCl

Product Specifications

CAS Number

1176758-02-3

Target

MMP, NMDAR

Related Pathways

Proteases/Proteasome, Neuroscience

Purity

1

Bioactivity

Otaplimastat HCl is a matrix metalloproteinase (MMP) inhibitor that blocks NMDA receptor-mediated excitotoxicity competitively and exhibits antioxidant activity, In oxygen-glucose-deprived endothelial cells, otaplimastat suppressed the activity rather than protein expression of MMPs by restoring the level of tissue inhibitor of metalloproteinase (TIMP) suppressed in ischemia, and consequently reduced vascular permeation. serving as a tool for research into brain ischemic injury and neuroprotection.

Smiles

Cl.O=C1NC=2C=CC=CC2C(=O)N1CCCNCCCCN(C(=O)C)CCCN3C(=O)NC=4C=CC=CC4C3=O

Molecular Formula

C28H35ClN6O5

Molecular Weight

571.07

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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