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SB 699551

Product Specifications

CAS Number

791789-61-2

Target

Akt, 5-HT Receptor, FOXO

Related Pathways

Apoptosis, PI3K/Akt/mTOR signaling, Neuroscience, GPCR/G Protein, Cytoskeletal Signaling

Purity

0.9983

Bioactivity

SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM), reduces phosphorylation levels of AKT and FOXO1, and exhibits inhibitory effects against breast cancer.

Smiles

O=C(N(CC=1C=CC(=CC1)C2=CC=C(C=C2)CNCCC=3C=CC=CC3)CCN(C)C)CCC4CCCC4

Molecular Formula

C34H45N3O

Molecular Weight

511.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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