2-Thio-UTP
Product Specifications
CAS Number
35763-29-2
Target
Others, P2Y Receptor
Related Pathways
Others, Neuroscience, GPCR/G Protein
Bioactivity
2-Thio-UTP is a selective P2Y2 receptor (purinergic receptor) agonist (EC50 = 50 nM) capable of inhibiting calcification potential, α-smooth muscle actin expression, and pro-fibrotic gene expression in valvular interstitial cells (VICs) . It may be employed in studies of calcific aortic valve stenosis (CAVS) .
Smiles
O[C@H]1[C@@H](O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O)N2C(=S)NC(=O)C=C2
Molecular Formula
C9H15N2O14P3S
Molecular Weight
500.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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