LY 2389575 hydrochloride
Product Specifications
CAS Number
885104-09-6
Target
Beta Amyloid, GluR
Related Pathways
Neuroscience
Purity
>99.99%
Bioactivity
LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of β-amyloid (Aβ), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease.
Smiles
N(CC1=C(Cl)C=C(Cl)C=C1)[C@@H]2CN(CC2)C=3N=CC(Br)=CN3.Cl
Molecular Formula
C15H16BrCl3N4
Molecular Weight
438.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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