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LY 2389575 hydrochloride

Product Specifications

CAS Number

885104-09-6

Target

Beta Amyloid|||GluR

Related Pathways

Neuroscience

Purity

>99.99%

Bioactivity

LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of ?-amyloid (A?), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease.

Smiles

N(CC1=C(Cl)C=C(Cl)C=C1)[C@@H]2CN(CC2)C=3N=CC(Br)=CN3.Cl

Molecular Formula

C15H16BrCl3N4

Molecular Weight

438.58

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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