What is the catalog number for TH301?

The catalog number for TH301 is T212591.

What sizes are available for TH301?

TH301 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TH301 come in?

TH301 is available in 2 different pack sizes.

TH301 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TH301?

TH301 is manufactured by Molfinity.

What is the estimated delivery time for TH301?

Estimated delivery time for TH301 is approximately 10 business day(s), depending on your location.

TH301

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

TH301 acts as a stabilizer for cryptochrome circadian regulator 2 (CRY2) . It demonstrates selectivity by stabilizing CRY2 over CRY1 in a degradation assay conducted with HEK293 cells expressing CRY reporters at concentrations ranging from 0.1 to 10 μM. In wild-type mouse fibroblasts, TH301 extends the circadian period, but this effect is absent in Cry2-/- fibroblasts. Additionally, it boosts rosiglitazone-dependent induction of brown adipose tissue-specific genes such as Ucp1, Cidea, and Kcnk3 in primary mouse stromal vascular fractions.