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PI3-Kinase Inhibitor

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

PI3-Kinase inhibitor targets PI3K? with an IC50 of 1.5 nM and shows selectivity over PI3K?, PI3K?, and PI3K?, exhibiting IC50 values of 3,333 nM, >10,000 nM, and >1,000 nM, respectively. At 100 mg/kg, it reduces tumor growth in a 4T1 murine mammary cancer model. In a mouse model of experimental autoimmune encephalomyelitis (EAE), it lessens disease severity when administered at doses of 20 or 80 mg/kg.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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