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Tubulin/VEGFR-2-IN-1

Product Specifications

Target

ROS|||Microtubule Associated|||VEGFR|||Apoptosis

Related Pathways

Cytoskeletal Signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Immunology/Inflammation|||Apoptosis

Bioactivity

Tubulin/VEGFR-2-IN-1 is a dual inhibitor of tubulin and VEGFR, with an IC50 of 1.52 ?M, demonstrating anti-angiogenic properties. It exhibits potent cytotoxic effects against cancer cells, elevates ROS production in HepG-2 cells, induces apoptosis and causes G0/G1 phase arrest. Additionally, it inhibits the migration and colony formation abilities of HepG-2 cells. Tubulin/VEGFR-2-IN-1 is applicable in cancer research.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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