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Antiproliferative agent-72

Product Specifications

CAS Number

1052646-54-4

Target

HSP

Related Pathways

Metabolism, Cytoskeletal Signaling

Bioactivity

Antiproliferative agent-72 (Compound 10) is an Hsp90 inhibitor with a dissociation constant (Kd) of 11 nM. It exhibits antiproliferative activity with IC50 values of 1.5 μM and 1.1 μM against HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 is suitable for cancer research applications.

Smiles

ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(=NC2=C4)N)=C3

Molecular Formula

C20H17Cl2N3O2S

Molecular Weight

434.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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