(GalNAc) 3-CPT
Product Specifications
Target
Phosphatase|||Apoptosis
Related Pathways
Metabolism|||Apoptosis
Bioactivity
(GalNAc) 3-CPT is a glycan-conjugated prodrug that targets the asialoglycoprotein receptor (ASGR) overexpressed on liver cells. It demonstrates significant antitumor activity by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumor sites, leading to apoptosis of tumor cells. In HepG2 cells, it shows an IC50 value of 3.07 ?M.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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