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PDE5-IN-15

Product Specifications

CAS Number

366444-83-9

Target

PDE

Related Pathways

Metabolism

Bioactivity

PDE5-IN-15 (compound 21) is a xanthine derivative and PDE5 inhibitor with IC50 values of 0.002 ?M for hPDE5, 0.180 ?M for bPDE6, 2.85 ?M for bPDE1, and 2.22 ?M for hPDE3. It exhibits good oral bioavailability in dogs and is applicable in research related to male erectile dysfunction.

Smiles

O=C1C=2NC(=NC2N(C(=O)N1C)CC(C)C)CC3=CN=CC4=CC=C(OC)C=C43

Molecular Formula

C21H23N5O3

Molecular Weight

393.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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